San Francisco, CA – May 8, 2014.  Station X and the Icahn School of Medicine at Mount Sinai will be presenting their collaborative, patient-oriented genomics research at The Cancer Genome Atlas' 3rd Annual Scientific Symposium to be held May 12-13, 2014 in Bethesda, MD at the National Institute of Health. Investigators from around the world will come together at this open scientific meeting to share their novel biological discoveries, analytical methods, and translational approaches using TCGA data in the context of collaborative workshops, poster sessions, and plenary presentations. 

Station X in collaboration with clinical researchers and physicians at the Icahn School of Medicine at Mount Sinai are using GenePool™ to rapidly mine thousands of patient-derived DNA samples to uncover mutations that are markers for breast and ovarian cancer susceptibility. A subset of the samples were collected by Drs. John A. Martignetti and Peter R. Dottino of Mount Sinai as part of an on-going clinical study investigating the genetics of patients with a strong family history of breast and ovarian cancers. The majority of the samples analyzed as part of this research study were generated by The Cancer Genome Atlas, a United States government-funded initiative that is generating over 2.5 petabytes of patient-derived, cancer genomics data encompassing over 25 different cancer types. The primary objective of this resource is to help improve our molecular understanding of various cancers and link that knowledge to patients' health profiles.

As rich as the TCGA resource is, it has been difficult for most cancer researchers and clinicians to work with this data primarily due to challenges in securely managing such a high volume of patient-derived data, the large amounts of computing power required, and the need to integrate medical knowledge & other biological data. GenePool is a scalable technology platform developed by Station X for securely managing, analyzing, and sharing genomic and clinical data. Station X recently launched GenePool Reference, a free resource for the research community to access and analyze a growing reference library of genomics data, which includes more than 7,000 TCGA-generated RNA-Seq samples. Station X also works with customers and collaborators interested in drawing insights from the controlled access mutation data by working together within the guidelines established by the National Institute of Health's Database of Genotypes and Phenotypes

Station X and Icahn School of Medicine at Mount Sinai will be presenting the results of their collaborative research powered by GenePool next week at the TCGA Symposium: 

Dr. John A. Martignetti, M.D., Ph.D, Associate Professor at the Icahn School of Medicine at Mount Sinai will present "Data Mining TCGA Breast and Ovarian Exomes for Novel Susceptibility Markers" as an oral presentation during Session IV of the TCGA Symposium on May 13th, 2014 at 11:35am. 

Dr. Sandeep Sanga, Ph.D., VP of Products at Station X will present "GenePool: A Cloud-based Genomics Software Platform Enabling Rapid Mining of TCGA Expression and Sequence Variation Data for the Cancer Research Community" as Poster #55 during the TCGA Symposium poster sessions held on May 12-13, 2014

For copies of the presentation or the poster, please contact