GenePool Helps the California Pacific Medical Center Research Institute Investigate the Role of Mitochondrial DNA Variants in Age-Related Disease.

At the California Pacific Medical Center Research Institute (CPMCRI) in San Francisco, California, scientist Gregory Tranah, PhD, is investigating how inherited and acquired alterations in mitochondrial DNA (mtDNA) contribute to the genetics and epidemiology of aging and age-related disease. Central to this work are several large-scale sequencing studies that Dr. Tranah and his colleagues hope will support the development of new medicines or clinical strategies that improve the care of elderly people.